Visit Prof. Raghavan’s google scholar profile for latest list of publications.

Inventions and Patents

  • Dickerhoff B, Kumar V, and Farivar RS, Raghavan ML, “Cellulose-based percutaneous Heart valve Prosthesis”, US Patents #WO2013119912A1
  • Schwarz C, Kumar V and Raghavan ML, “Methods of producing biosynthetic bacterial cellulose membranes”, US patents # WO2017100771A1

Peer-reviewed Journal Articles

Last update on March 20, 2023

  • Raghuram A, Galloy A, Nino M, Sanchez S, Hasan D, Raghavan S, Samaniego EA. Comprehensive morphomechanical analysis of brain aneurysms. Acta Neurochirurgica. Jan 3:1-0, 2023, In press.
  • Sanchez, S., Hickerson, M., Patel, R.R., Ghazaleh, D., Tarchand, R., Paranjape, G.S., Pope, H., Ortega‐Gutierrez, S., Pederson, J.M., Hasan, D. and Raghavan, M.L., Samaniego EA., Morphological Characteristics of Ruptured Brain Aneurysms: A Systematic Literature Review and Meta‐Analysis." Stroke: Vascular and Interventional Neurology (2023): e000707.
  • AE Galloy, RE Amelon, JM Reinhardt, ML Raghavan, Contact mechanics model of lung lobar sliding, Applications in Engineering Science, 10: 100098, 2022
  • Chu JH, Sarathy S, Ramesh S, Rudolph K, Raghavan ML, Badheka A. Risk factors for hemolysis with centrifugal pumps in pediatric extracorporeal membrane oxygenation: Is pump replacement an answer? Perfusion. 2022, in press. 
  • Sarathy S, Turek JW, Chu J, Badheka A, Nino MA, Raghavan ML. Flow monitoring of ECMO circuit for detecting oxygenator obstructions. Ann Biomed Enngineering. 2021, 49:3636-3646.
  • Sarathy S, Nino MA, Ghanim AH, Rajagopal S, Mubeen S, Raghavan ML. Electrochemical Approach to Measure Physiological Fluid Flow Rates. Front Chem. 9: 680099, 2021.
  • Polzer S, Kracík J, Novotný T, Kubíček L, Staffa R, Raghavan ML. Methodology for Estimation of Annual Risk of Rupture for Abdominal Aortic Aneurysm. Comput Methods Programs Biomed., 200: 105916, 2021
  • Raghuram A, Varon A, Roa JA, et al. Semiautomated 3D mapping of aneurysmal wall enhancement with 7T-MRI. Sci Rep. 2021;11(1):1-13.
  • Galloy AE, Raghuram A, Nino MA, et al. Analysis of Cerebral Aneurysm Wall Tension and Enhancement Using Finite Element Analysis and High-Resolution Vessel Wall Imaging. Front Neurol. 2021;12: 2263 In press.
  • Polzer S, Man V, Vlachovský R, Raghavan ML, Failure properties of abdominal aortic aneurysm tissue are orientation dependent. J Mech Behav Biomed Mater. 2021;114:104181.
  • Sabotin RP, Varon A, Roa JA, et al. Insights into the pathogenesis of cerebral fusiform aneurysms: high-resolution MRI and computational analysis. J Neurointerv Surg., 13 (12), 1180-1186, 2021
  • Gomes VC, da Silva LFF, Raghavan ML, et al. Biomechanical and histological data from abdominal aortas harvested in autopsy. Data Br. 2021;35:106953.
  • Gomes VC, Raghavan ML, da Silva LFF, et al. Experimental study of rupture pressure and elasticity of abdominal aortic aneurysms found at autopsy. Ann Vasc Surg. 2021;70:517-527.
  • S Attarian, S Xiao, TC Chung, ES da Silva, ML Raghavan, “Investigation of the Observed Rupture Lines in Abdominal Aortic Aneurysms Using Crack Propagation Simulations”, Journal of biomechanical engineering 141 (7), 2020
  • JS Hudson, TK Chung, BS Prout, Y Nagahama, ML Raghavan, DM Hasan, “Iron nanoparticle contrast enhanced microwave imaging for emergent stroke: A pilot study”, Journal of Clinical Neuroscience 59, 284-290, 2019
  • Nakagawa D, Kudo K, Awe O, Zanaty M, Nagahama Y, Cushing C, Magnotta V, Hayakawa M, Allan L, Greenlee J, Awad IA, Carroll T, Torner J, Raghavan ML, Hasan DM , “Detection of microbleeds associated with sentinel headache using MRI quantitative susceptibility mapping: pilot study”, Journal of Neurosurgery, 1 (aop), 1-7, 2018
  • Schumacher AL, Gilmer CM, Atlurui K, Lee J, Jugessur AS, Salem AK, Bowden NB, Raghavan ML, Hasan DM, “Development and Evaluation of a Nanometer-Scale Hemocompatible and Antithrombotic Coating Technology Platform for Commercial Intracranial Stents and Flow Diverters”, ACS Appl. Nano Mater., 1 (1), pp 344–354, 2018
  • Nakagawa D, Nagahama Y, Policeni BA, Raghavan ML, Dillard SI, Schumacher AL, Sarathy S, Dlouhy BJ, Wilson S, Allan L, Woo HH, Huston III J, Cloft HJ, Wintermark M, Torner JC, Brown Jr RD, Hasan DM, “Accuracy of detecting enlargement of aneurysms using different MRI modalities and measurement protocols”, Journal of Neurosurgery, 2018, in press.
  • Chung TK, da Silva ES, Raghavan ML, “Does elevated wall tension cause aortic aneurysm rupture? Investigation using a subject-specific heterogeneous model”, Journal of biomechanics 64, 164-171, 2017
  • Mocco J, Brown RD, Torner JC, Capuano AW, Fargen KW, Raghavan ML, Piepgras DG, Meissner I, “Aneurysm morphology and prediction of rupture: an international study of unruptured intracranial aneurysms analysis”, Neurosurger, 82(4):491-496, 2018
  • Badheka A, Stucker SE, Turek JW, Raghavan ML., “Efficacy of Flow monitoring during ECMO”, ASAIO Journal, (in print), 2017
  • Nellis JR, Chung TK, Agarwal N, Torres JE, Holgren SE, Raghavan ML, Turek JW., “Modeling Outcomes: Modified Aortic Arch Advancement for Neonatal Hypoplastic Arch”, Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery, 12(2):109-115, 2017
  • Ramachandran M, Retarekar R, Raghavan ML, Berkowitz B, Dickerhoff B, Correa T, Lin S, Johnson K, Hasan D, Ogilvy C, Rosenwasser R, Torner J, Bogason E, Stapleton CJ, Harbaugh RE., “Assessment of image-derived risk factors for natural course of unruptured cerebral aneurysms”, J Neurosurg. 124(2):288-295, 2016
  • NC Batagini, CAP Ventura, ML Raghavan, MC Chammas, A Tachibana, “Volumetry and biomechanical parameters detected by 3D and 2D ultrasound in patients with and without an abdominal aortic aneurysm”, Vascular Medicine 21 (3), 209-216, 2016
  • AL Hoppe, ML Raghavan, DM Hasan , “Comparison of the association of sac growth and coil compaction with recurrence in coil embolized cerebral aneurysms” PloS one 10 (4), e0123017, 2015
  • Ninomiya OH, Tavares Monteiro JA, Higuchi Mde L, Puech-Leão P, de Luccia N, Raghavan ML, da Silva ES., “Biomechanical Properties and Microstructural Analysis of the Human Nonaneurysmal Aorta as a Function of Age, Gender and Location: An Autopsy Study”, J Vasc Res., 52(4):257-64, 2015
  • Dillard SI, Mousel JA, Shrestha L, Raghavan ML, Vigmostad SC, “From medical images to flow computations without user-generated meshes”, Int J Numer Method Biomed Eng. 2014 EPub ahead of print, 2014
  • Retarekar R, Ramachandran M, Berkowitz B, Harbaugh RE, Hasan D, Rosenwasser RH, Ogilvy CS, Raghavan ML, “Stratification of a population of intracranial aneurysms using blood flow metrics”, Comput Methods Biomech Biomed Engin. 2014 EPub ahead of print, 2014
  • Raghavan ML, Sharda GV, Huston J 3rd, Mocco J, Capuano AW, Torner JC, Saha PK, Meissner I, Brown RD Jr; International Study of Unruptured Intracranial Aneurysms Investigators, “Aneurysm shape reconstruction from biplane angiograms in the ISUIA collection”, Transl Stroke Res, 5(2):252-9, 2014
  • Amelon RE, Cao K, Reinhardt JM, Christensen GE, Raghavan ML, “A measure for characterizing sliding on lung boundaries”, Ann Biomed Eng, 42(3):642-50, 2014
  • Monteiro JAT, da Silva ES, Raghavan ML, Puech-Leão P, Higuchi ML, Otoch JP, “Histological, histochemical and biomechanical properties of fragments isolated from the anterior wall of abdominal aortic aneurysms”, Journal of Vascular Surgery, 59(5):1393-1401, 2014
  • (Invited comment) A Hoppe, ML Raghavan, RE Harbaugh, “Comment RE: Computational Fluid Dynamic Analysis of Intracranial Aneurysmal Bleb Formation”, Neurosurgery, 73 (6):1068-1069, 2013
  • J Lu, S Hu, ML Raghavan, “A Shell-Based Inverse Approach of Stress Analysis in Intracranial Aneurysms”, Annals of Biomedical Engineering, 41(7):1505-15, 2013
  • Ramachandran, R, Retarekar R, Harbaugh RE, Hasan D, Policeni B, Rosenwasser R, Ogilvy C, and Raghavan ML, "Sensitivity of Quantified Intracranial Aneurysm Geometry to Imaging Modality", Cardiovascular Engineering and Technology, 2013, DOI: 10.1007/s13239-013-0119-9
  • Cao K, Christensen GE, Ding K, Du K, Raghavan ML, Amelon RE, Baker KM, Hoffman EA, Reinhardt JM, “Tracking regional tissue volume and function change in lung using image registration”, Int J Biomed Imaging. 2012; Epub 2012
  • Ramachandran M, Laakso A, Harbaugh RE, Raghavan ML, “On the role of modeling choices in estimation of cerebral aneurysm wall tension”, J Biomech, 15;45(16):2914-9, 2012
  • Harbaugh RE, Raghavan ML, Ramachandran M, Rahman M, Hoh BL, “Comments RE: Ruptured status discrimination performance of aspect ratio, height/width, and bottleneck factor is highly dependent on aneurysm sizing methodology”, Neurosurgery. 2012 Jul;71(1):45-6.
  • Lin KK, Kratzberg JA, Raghavan ML, “Role of aortic stent graft oversizing and barb characteristics on folding”, J Vasc Surg., 55(5):1401-9, 2012
  • Laaksamo E, Ramachandran M, Frösen J, Tulamo R, Baumann M, Friedlander RM, Harbaugh RE, Hernesniemi J, Niemelä M, Raghavan ML, Laakso A., “Intracellular signaling pathways and size, shape, and rupture history of human intracranial aneurysms”, Neurosurgery, Jun;70(6):1565-72, 2012
  • Hasan DM, Nadareyshvili AI, Hoppe AL, Mahaney KB, Kung DK, Raghavan ML., "Cerebral aneurysm sac growth as the etiology of recurrence after successful coil embolization", Stroke, Mar;43(3):866-8, 2012
  • Amelon R, Cao K, Ding K, Christensen GE, Reinhardt JM, Raghavan ML, “Three-dimensional characterization of regional lung deformation”, J Biomech, 44(13):2489-95, 2011
  • Raghavan ML, Hanaoka MM, Kratzberg JA, Higuchi Mde L, da Silva ES, “Biomechanical failure properties and microstructural content of ruptured and unruptured abdominal aortic aneurysms”, J Biomech, 44(13):2501-7, 2011
  • Raghavan ML, Lin K, Ramachandran M, Nadareshvili A, Amelon RE, Lu J, “Planar radial extension for constitutive modeling of anisotropic biological soft tissues”, International Journal of structural changes in solids (accepted for publication), 3(2):23-31, 2011
  • Zhao X, Raghavan ML, Lu J, “Characterizing heterogeneous properties of cerebral aneurysms with unknown stress-free geometry: a precursor to in vivo identification”, J Biomech Eng, May;133(5):051008, 2011
  • Zhao X, Raghavan ML, Lu J, “Identifying heterogeneous anisotropic properties in cerebral aneurysms: a pointwise approach”, Biomech Model Mechanobiol., 10(2):177-89, 2011
  • Ding K, Cao K, Amelon RE, Raghavan ML, Christensen GE, and Reinhardt JM, “Comparison of Intensity- and Jacobian-Based Estimates of Lung Regional Ventilation” In M. Brown, M. de Bruijne, B. van Ginneken, K. Ding, A. Kiraly, J.-M. Kuhnigk, J. R. McClelland, K. Mori, and J. M. Reinhardt, eds., Third International Workshop on Pulmonary Image Analysis, pp. 49-60, Beijing, 2010
  • Cao K, Ding K, Christensen GE, Raghavan ML, Amelon RE, and Reinhardt JM, “Unifying Vascular Information in Intensity-Based Nonrigid Lung CT Registration”,  4th International Workshop on Biomedical Image Registration, pp. 1-12, Lubeck, Germany, 2010
  • Zhou X, Raghavan ML, Harbaugh RE, Lu J , “Patient-Specific Wall Stress Analysis in Cerebral Aneurysms Using Inverse Shell Model”, Ann Biomed Eng, 38(2):478-89, 2010
  • Cai ZJ, Bai EW, McCabe R, Zerhouni M, Wang G, Raghavan ML, Kratzberg J, “A dynamic arterial tree phantom for studies of bolus chasing CT angiography”, International Journal of Biomedical Engineering and Technology, 4(10):88-100, 2009
  • Kratzberg JA, Golzarian J, Raghavan ML, “Role of graft oversizing in the fixation strength of barbed endovascular grafts”, Journal of Vascular Surgery, 49(6): 1543-53, 2009
  • Kratzberg JA, Walker PJ, Rikkers E, and Raghavan ML, “The effect of proteolytic treatment on plastic deformation of porcine aortic tissue”, Journal of the Mechanical Behavior of Biomedical Materials, 2[1]:65-72, 2009.
  • Ding K, Cao K, Christensen GE, Raghavan ML, Hoffman EA, and Reinhardt JM, “Registration-based lung tissue mechanics assessment during tidal breathing”, In M. Brown, M. de Bruijne, B. van Ginneken, A. Kiraly, J.-M. Kuhnigk, C. Lorenz, K. Mori, and J. M. Reinhardt, eds., First International Workshop on Pulmonary Image Analysis, pp. 63-72, New York, 2008
  • Lu J, Zhou X, Raghavan ML., “Inverse method of stress analysis for cerebral aneurysms”, Biomech Model Mechanobiol, 7(6):477-86, 2008.
  • Zhang J, Fletcher JG, Vrtiska TJ, Manduca A, Thompson JL, Raghavan ML, Wentz RJ, McCollough CH., Large-vessel distensibility measurement with electrocardiographically gated multidetector CT: phantom study and initial experience. Radiology. 2007 Oct;245(1):258-66.
  • Lu J, Zhou X, Raghavan ML, “Inverse Elastostatic Stress Analysis in Pre-deformed Biological Structures: Demonstration Using Abdominal Aortic Aneurysms”, Journal of Biomechanics, 40(3):693-6, 2007
  • Ma, B, Lu J, Harbaugh RE, Raghavan ML, “Nonlinear Anisotropic Stress Analysis of Anatomically Realistic Cerebral Aneurysms”, Journal of Biomechanical Engineering, 129(1):88-96, 2007
  • Lu J, Zhou X, Raghavan ML, “Computational Method for Inverse Elastostatics in Anisotropic Hyperelastic Solids”, Journal for Numerical Methods in Engineering, 69: 1239-61, 2007
  • Raghavan, M.L., J. Kratzberg, E.M. Castro de Tolosa, M.M. Hanaoka, P. Walker, and E.S. da Silva, “Regional distribution of wall thickness and failure properties of human abdominal aortic aneurysm”, Journal of Biomechanics, 39(16):3010-6, 2006.
  • Raghavan ML, Ma B, Fillinger MF, “Non-invasive determination of zero-pressure geometry of arterial aneurysms”, Annals of Biomedical Engineering, 34(9):1414-9, 2006
  • Raghavan, M.L., M.F. Fillinger, S.P. Marra, B.P. Naegelein, and F.E. Kennedy, “Automated methodology for determination of stress distribution in human abdominal aortic aneurysm”, Journal of Biomechanical Engineering, 2005 Oct;127(5):868-71.
  • Raghavan ML, Kratzberg JA, Golzarian J., “Introduction to biomechanics related to endovascular repair of abdominal aortic aneurysm”, Techniques in Vascular Interventional Radiology, 8(1):50-5, 2005
  • Raghavan, M.L., B. Ma, and R.E. Harbaugh, “Quantified Aneurysm Shape and Rupture Risk”, Journal of Neurosurgery, 2005. 102(2): p. 355-62.
  • Ma B, Harbaugh RE, and Raghavan ML, “Three-dimensional Geometric characterization of cerebral aneurysms”, Annals of Biomedical Engineering, 32:264-273, 2004
  • Kratzberg JL, S. Greifzu, K. Larson, J. Dittman, M. McCormick, M. Keller, M.L. Raghavan, “Fabrication of a patient-specific replica of abdominal aortic aneurysm with realistic compliance and translucency”, International Journal of Cardiovascular Medicine, 5(1): 33-38, 2005
  • Raghavan ML, Trivedi S, Nagaraj A, McPherson DD, and Chandran KB, “Three-dimensional Finite Element Analysis of Residual Stress distribution in Arteries”, Annals of Biomedical Engineering, 32:257-263, 2004
  • Fillinger MF. Marra SP. Raghavan ML. Kennedy FE, “Prediction of rupture risk in abdominal aortic aneurysm during observation: wall stress versus diameter”, Journal of Vascular Surgery. 37(4):724-32, 2003
  • Fillinger, MF, Raghavan ML, Marra SP, Cronenwett JL, Kennedy FE, “In Vivo Analysis of Mechanical Wall Stress and AAA Rupture Risk”, Journal of Vascular Surgery, 36(3): 589-597, 2002
  • Raghavan ML, Vorp DA. Toward a biomechanical tool to evaluate rupture potential of abdominal aortic aneurysm: identification of a finite strain constitutive model and evaluation of its applicability. Journal of Biomechanics. 33(4): 475-82, Apr 2000
  • Raghavan ML, Vorp DA, Federle MP, Makaroun MS, Webster MW. Wall stress distribution on three-dimensionally reconstructed models of human abdominal aortic aneurysm. Journal of Vascular Surgery. 31(4): 760-9, Apr 2000
  • Sacks MS, Vorp DA, Raghavan ML, Federle MP, Webster MW. In vivo three-dimensional surface geometry of abdominal aortic aneurysms. Annals of Biomedical Engineering. 27(4): 469-79, 1999
  • Vorp DA, Raghavan ML, Webster MW. Mechanical wall stress in abdominal aortic aneurysm: influence of diameter and asymmetry. Journal of Vascular Surgery. 27(4): 632-9, Apr 1998
  • Raghavan ML, Webster MW, Vorp DA. Ex vivo biomechanical behavior of abdominal aortic aneurysm: assessment using a new mathematical model. Annals of Biomedical Engineering. 24(5): 573-82, 1996
  • Vorp DA, Raghavan ML, Muluk SC, Makaroun MS, Steed DL, Shapiro R, Webster MW. Wall strength and stiffness of aneurysmal and nonaneurysmal abdominal aorta. Annals of the New York Academy of Sciences. 800: 274-6, Nov 1996
  • Vorp DA, Raghavan ML, Borovetz HS, Greisler HP, Webster MW. Modeling the transmural stress distribution during healing of bioresorbable vascular prostheses. Annals of Biomedical Engineering. 23(2): 178-88, 1995